Joint pain blood tests: uric acid, arthritis markers and vitamins

Joint pain can come from wear and tear, an old injury, or from conditions like gout and rheumatoid arthritis where blood tests are very useful. The pattern matters: sudden pain in the big toe points one way, morning stiffness in both hands another. Blood tests help your doctor separate these and decide whether you need a specialist.

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Tests to ask about

Uric acid

High levels are linked with gout attacks.

₹210 Book Details

RA factor

A first screening test when rheumatoid arthritis is suspected.

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Anti-CCP

More specific for rheumatoid arthritis than RA factor.

₹1,550 Book Details

CRP (C-reactive protein)

Shows if there is active inflammation in the body.

₹525 Book Details

Vitamin D (25-OH)

Low levels are commonly linked with bone and joint aches.

₹1,300 Book Details

Calcium

Checked along with vitamin D for bone health.

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Common reasons doctors look for

High uric acid (gout) – sudden painful, red joint, often big toe
Rheumatoid arthritis – morning stiffness in small joints of both hands
Age-related wear (osteoarthritis) of knees
Low vitamin D or calcium
Joint pain after viral fevers like chikungunya
Thyroid problems

How to prepare

Most joint tests need no fasting. For uric acid, avoid a heavy non-veg meal or alcohol the night before. If a lipid profile or fasting sugar is in your package, fast 10–12 hours.

When to see a doctor

See a doctor quickly if a joint becomes hot, red and very swollen with fever – this can be a joint infection. Also see a doctor for joint pain after a fall, inability to bear weight, or joint pain with rash, mouth ulcers or eye redness.

Joint Pain – FAQs

Which blood test is done for joint pain?

Common tests are uric acid, RA factor, anti-CCP, CRP, ESR, vitamin D and calcium. Your doctor picks them based on which joints hurt and how.

Does a positive RA factor mean I have arthritis?

Not always. RA factor can be positive in some healthy people and other conditions. Doctors combine it with anti-CCP, symptoms and examination.

Is high uric acid always gout?

No. Many people have high uric acid without pain. Gout is diagnosed when there are typical attacks; your doctor will interpret it.

Can vitamin D deficiency cause joint pain?

Low vitamin D is commonly linked with bone and muscle aches. A blood test shows if your level is low.

This page is general information, not medical advice or a diagnosis. Please talk to a doctor about your symptoms.

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PREGNANCY (2)
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ALLERGY 1TOTAL IGE
ANEMIA 1RETICULOCYTE COUNT (%)
ARTHRITIS 6ANTI CCP (ACCP)ANTI NUCLEAR ANTIBODIES (ANA)COMPLEMENT 4 (C4)PHOSPHOROUSRHEUMATOID FACTOR (RF)ANA TITRE (IMMUNOFLUORESCENCE)
AUTOIMMUNITY 7ANTI THYROGLOBULIN ANTIBODY (ATG)COMPLEMENT 3 (C3)ANTI - DSDNAIMMUNOGLOBULIN A (IGA)IMMUNOGLOBULIN G (IGG)IMMUNOGLOBULIN M (IGM)TISSUE TRANSGLUTAMINASE - IGA (TTG)
CANCER MARKERS 4CA-125CA 15.3CA 19.9CARCINO EMBRYONIC ANTIGEN (CEA)
CARDIAC 1NT-PROBNP
CARDIAC RISK MARKERS 10APO B / APO A1 RATIO (APO B/A1)APOLIPOPROTEIN - A1 (APO-A1)APOLIPOPROTEIN - B (APO-B)C-REACTIVE PROTEIN (CRP)HOMOCYSTEINEHIGH SENSITIVITY C-REACTIVE PROTEIN (HS-CRP)LACTATE DEHYDROGENASE (LDH)Lipoprotein (a) [Lp(a)]LP-PLA2SMALL DENSE LDL
COMPLETE HEMOGRAM 30BASOPHILS - ABSOLUTE COUNTEOSINOPHILS - ABSOLUTE COUNTLYMPHOCYTES - ABSOLUTE COUNTMONOCYTES - ABSOLUTE COUNTNEUTROPHILS - ABSOLUTE COUNTBASOPHILSEOSINOPHILSHEMOGLOBINIMMATURE GRANULOCYTES(IG)IMMATURE GRANULOCYTE PERCENTAGE(IG%)TOTAL LEUCOCYTES COUNT (WBC)LYMPHOCYTEMEAN CORPUSCULAR HEMOGLOBIN(MCH)MEAN CORP.HEMO.CONC(MCHC)MEAN CORPUSCULAR VOLUME(MCV)MENTZER INDEXMONOCYTESMEAN PLATELET VOLUME(MPV)NEUTROPHILSNUCLEATED RED BLOOD CELLSNUCLEATED RED BLOOD CELLS %PLATELETCRIT(PCT)HEMATOCRIT(PCV)PLATELET DISTRIBUTION WIDTH(PDW)PLATELET TO LARGE CELL RATIO(PLCR)PLATELET COUNTTOTAL RBCRED CELL DISTRIBUTION WIDTH (RDW-CV)RED CELL DISTRIBUTION WIDTH INDEX (RDWI)RED CELL DISTRIBUTION WIDTH - SD(RDW-SD)
COMPLETE URINE ANALYSIS 24SPECIFIC GRAVITYAPPEARANCEBACTERIAURINARY BILIRUBINURINE BLOODUROBILINOGENBILE PIGMENTBILE SALTCASTSCOLOURCRYSTALSEPITHELIAL CELLSURINARY GLUCOSEURINE KETONELEUCOCYTE ESTERASEURINARY LEUCOCYTES (PUS CELLS)MUCUSNITRITEPARASITEPHURINARY PROTEINRED BLOOD CELLSVOLUMEYEAST
DIABETES 7AVERAGE BLOOD GLUCOSE (ABG)C-PEPTIDEFASTING BLOOD SUGAR(GLUCOSE)HbA1cHOMA INSULIN RESISTANCE INDEXINSULIN - FASTINGURINARY MICROALBUMIN
ELECTROLYTE 1BICARBONATE
ELECTROLYTES 3CHLORIDEPOTASSIUMSODIUM
HEMATOLOGY 1TROPONIN I HEART ATTACK RISK
HEPATITIS PANEL 1ANTI HEPATITIS C VIRUS (ANTI HCV) - TOTAL
HORMONE 2CORTISOL SERUM (MORNING SAMPLE 6AM -10AM)TESTOSTERONE
INFECTION 1HELICOBACTER PYLORI - IGG
INFECTIOUS DISEASES 3HIV I and IIHEPATITIS B SURFACE ANTIGEN (HBSAG)VDRL (RPR) FOR SYPHILIS
INFERTILITY 817 OH PROGESTERONEANTI MULLERIAN HORMONE (AMH)DHEA - SULPHATE (DHEAS)FOLLICLE STIMULATING HORMONE (FSH)FREE TESTOSTERONELUTEINISING HORMONE (LH)PROLACTIN (PRL)SEX HORMONE BINDING GLOBULIN (SHBG)
IRON DEFICIENCY 5% TRANSFERRIN SATURATIONFERRITINIRONTOTAL IRON BINDING CAPACITY (TIBC)UNSAT.IRON-BINDING CAPACITY(UIBC)
LIPID 10TOTAL CHOLESTEROLHDL CHOLESTEROL - DIRECTHDL / LDL RATIOLDL CHOLESTEROL - DIRECTLDL / HDL RATIONON-HDL CHOLESTEROLTC/ HDL CHOLESTEROL RATIOTRIG / HDL RATIOTRIGLYCERIDESVLDL CHOLESTEROL
LIVER 12SERUM ALB/GLOBULIN RATIOALKALINE PHOSPHATASEBILIRUBIN -DIRECTBILIRUBIN (INDIRECT)BILIRUBIN - TOTALGAMMA GLUTAMYL TRANSFERASE (GGT)SGOT / SGPT RATIOPROTEIN - TOTALALBUMIN - SERUMSERUM GLOBULINASPARTATE AMINOTRANSFERASE (SGOT )ALANINE TRANSAMINASE (SGPT)
METABOLIC 1MAGNESIUM
OTHER COUNTS 1ERYTHROCYTE SEDIMENTATION RATE (ESR)
PANCREATIC 2AMYLASELIPASE
Pregnancy 1ALPHA FETO PROTEIN
PREGNANCY 3BETA HCGESTRADIOL/OESTROGEN (E2)PROGESTERONE
RENAL 8BUN / Sr.CREATININE RATIOBLOOD UREA NITROGEN (BUN)CALCIUMCYSTATIN CCREATININE - SERUMUREA / SR.CREATININE RATIOUREA (CALCULATED)URIC ACID
THYROID 8Anti-TPO antibody (Anti-Thyroid Peroxidase)CALCITONINFREE TRIIODOTHYRONINE (FT3)FREE THYROXINE (FT4)TOTAL TRIIODOTHYRONINE (T3)TOTAL THYROXINE (T4)THYROGLOBULIN (TG)TSH - ULTRASENSITIVE
TOXIC ELEMENTS 14ALUMINIUMARSENICBARIUMCADMIUMCOBALTCHROMIUMCOPPERMERCURYMANGANESENICKELLEADSELENIUMTHALLIUMZINC
VITAMIN 8VITAMIN AVITAMIN B-12VITAMIN B1/THIAMINVITAMIN B2/RIBOFLAVINVITAMIN B6/PYRIDOXAL - 5 - PHOSPHATEVITAMIN B9/FOLIC ACID25-OH VITAMIN D (TOTAL)VITAMIN E